Queen Elizabeth in Geirangerfjord, Norway, with steep green mountains behind

21-Night Greek Isles and Eastern Mediterranean from Barcelona on Queen Elizabeth

Nights: 21
Ports of call: 14 to 15
Departures: 8
From: $2,589

Queen Elizabeth sails this route from the Port of Barcelona 8 times in the window we track. Each one runs 21 nights. It finishes in Trieste (Italy) rather than back in Barcelona, so check flights home before you book.

Every sailing calls at Civitavecchia (Italy) and Zadar (Croatia). The other ports change with the date: there are 8 port combinations, each listed below with its own departure dates. We record which ports a sailing visits, not the order it visits them in.

Departures run from Fri, May 14, 2027 to Fri, Sep 15, 2028. The cheapest recorded starting fare is $2,589 per person, which works out at $123 a night.

Our Mediterranean guide covers which Italian, French and Greek ports each length of cruise reaches, and how the lines differ.

Schedule last updated 2026-11-04 · 8 departures listed · Dates can change. Verify with the cruise line before booking.

Which ports, on which dates?

Via Mykonos

Calls at Messina (Sicily, Italy) · Piraeus (Greece) · Dardanelles (Turkey) · Istanbul (Turkey) · Dardanelles (Turkey) · Ephesus (Turkey) · Mykonos (Greece) · Katakolon (Greece) · Messina (Sicily, Italy) · Sorrento (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia)

1 departure, from $3,429 per person

Fri, May 14, 2027

Via Palma de Mallorca and Kefalonia

Calls at Valencia (Spain) · Palma de Mallorca (Spain) · Ajaccio (Corsica, France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy)

1 departure, from $2,589 per person

Fri, Jun 11, 2027

Via Ajaccio and Ibiza

Calls at Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · La Spezia (Italy) · Ajaccio (Corsica, France) · Ibiza (Spain) · Palma de Mallorca (Spain)

1 departure, from $2,799 per person

Fri, Aug 20, 2027

Via Rhodes

Calls at Messina (Sicily, Italy) · Piraeus (Greece) · Dardanelles (Turkey) · Istanbul (Turkey) · Dardanelles (Turkey) · Ephesus (Turkey) · Rhodes (Greece) · Katakolon (Greece) · Messina (Sicily, Italy) · Civitavecchia (Italy) · Palermo (Sicily, Italy) · Messina (Sicily, Italy) · Corfu (Greece) · Korcula (Croatia) · Zadar (Croatia)

1 departure, from $2,669 per person

Fri, Oct 1, 2027

Via Valencia and Santa Margherita

Calls at Valencia (Spain) · Ajaccio (Corsica, France) · Santa Margherita (Italy) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy)

1 departure, from $3,849 per person

Fri, Jun 23, 2028

Via Calvi

Calls at Ibiza (Spain) · Marseille (France) · Calvi (France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Palma de Mallorca (Spain)

1 departure, from $3,599 per person

Fri, Aug 4, 2028

Via Bari

Calls at Ibiza (Spain) · Marseille (France) · Santa Margherita (Italy) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Bari (Italy) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Naples (Italy)

1 departure, from $3,649 per person

Fri, Aug 25, 2028

Via Valencia and Marseille

Calls at Valencia (Spain) · Marseille (France) · Ajaccio (Corsica, France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Korcula (Croatia) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Palma de Mallorca (Spain)

1 departure, from $3,909 per person

Fri, Sep 15, 2028

Every departure on this route

We may earn a commission if you book through these buttons, at no cost to you.

21-Night Greek Isles and Eastern Mediterranean departures on Queen Elizabeth
Departs	Nights	Itinerary & ports	From
Fri, May 14, 2027 ends Fri, Jun 4, 2027 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Messina (Sicily, Italy) · Piraeus (Greece) · Dardanelles (Turkey) · Istanbul (Turkey) · Dardanelles (Turkey) · Ephesus (Turkey) · Mykonos (Greece) · Katakolon (Greece) · Messina (Sicily, Italy) · Sorrento (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) Ends in Trieste (Italy)	from $3,429 $163 a night · per person ocean view, as of 2026-11-04
Fri, Jun 11, 2027 ends Fri, Jul 2, 2027 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Valencia (Spain) · Palma de Mallorca (Spain) · Ajaccio (Corsica, France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) Ends in Civitavecchia (Italy)	from $2,589 $123 a night · per person interior, as of 2026-11-04 Lowest fare shown
Fri, Aug 20, 2027 back Fri, Sep 10, 2027 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · La Spezia (Italy) · Ajaccio (Corsica, France) · Ibiza (Spain) · Palma de Mallorca (Spain)	from $2,799 $133 a night · per person interior, as of 2026-11-04
Fri, Oct 1, 2027 ends Fri, Oct 22, 2027 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Messina (Sicily, Italy) · Piraeus (Greece) · Dardanelles (Turkey) · Istanbul (Turkey) · Dardanelles (Turkey) · Ephesus (Turkey) · Rhodes (Greece) · Katakolon (Greece) · Messina (Sicily, Italy) · Civitavecchia (Italy) · Palermo (Sicily, Italy) · Messina (Sicily, Italy) · Corfu (Greece) · Korcula (Croatia) · Zadar (Croatia) Ends in Trieste (Italy)	from $2,669 $127 a night · per person interior, as of 2026-11-04
Fri, Jun 23, 2028 ends Fri, Jul 14, 2028 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Valencia (Spain) · Ajaccio (Corsica, France) · Santa Margherita (Italy) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) Ends in Civitavecchia (Italy)	from $3,849 $183 a night · per person interior, as of 2026-11-04
Fri, Aug 4, 2028 back Fri, Aug 25, 2028 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Ibiza (Spain) · Marseille (France) · Calvi (France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Palma de Mallorca (Spain)	from $3,599 $171 a night · per person interior, as of 2026-11-04
Fri, Aug 25, 2028 back Fri, Sep 15, 2028 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Ibiza (Spain) · Marseille (France) · Santa Margherita (Italy) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Bari (Italy) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Naples (Italy)	from $3,649 $174 a night · per person interior, as of 2026-11-04
Fri, Sep 15, 2028 back Fri, Oct 6, 2028 Terminal not published yet	21	21-Night Greek Isles and Eastern Mediterranean Calls at Valencia (Spain) · Marseille (France) · Ajaccio (Corsica, France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Korcula (Croatia) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Palma de Mallorca (Spain)	from $3,909 $186 a night · per person interior, as of 2026-11-04

MAY
14
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Messina (Sicily, Italy) · Piraeus (Greece) · Dardanelles (Turkey) · Istanbul (Turkey) · Dardanelles (Turkey) · Ephesus (Turkey) · Mykonos (Greece) · Katakolon (Greece) · Messina (Sicily, Italy) · Sorrento (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia)
Ends in Trieste (Italy)
Ends Fri, Jun 4, 2027 in Trieste
from $3,429 $163 a night · per person
ocean view, as of 2026-11-04
JUN
11
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Valencia (Spain) · Palma de Mallorca (Spain) · Ajaccio (Corsica, France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy)
Ends in Civitavecchia (Italy)
Ends Fri, Jul 2, 2027 in Civitavecchia
Lowest fare shown
from $2,589 $123 a night · per person
interior, as of 2026-11-04
AUG
20
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · La Spezia (Italy) · Ajaccio (Corsica, France) · Ibiza (Spain) · Palma de Mallorca (Spain)
Returns Fri, Sep 10, 2027
from $2,799 $133 a night · per person
interior, as of 2026-11-04
OCT
1
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Messina (Sicily, Italy) · Piraeus (Greece) · Dardanelles (Turkey) · Istanbul (Turkey) · Dardanelles (Turkey) · Ephesus (Turkey) · Rhodes (Greece) · Katakolon (Greece) · Messina (Sicily, Italy) · Civitavecchia (Italy) · Palermo (Sicily, Italy) · Messina (Sicily, Italy) · Corfu (Greece) · Korcula (Croatia) · Zadar (Croatia)
Ends in Trieste (Italy)
Ends Fri, Oct 22, 2027 in Trieste
from $2,669 $127 a night · per person
interior, as of 2026-11-04
JUN
23
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Valencia (Spain) · Ajaccio (Corsica, France) · Santa Margherita (Italy) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy)
Ends in Civitavecchia (Italy)
Ends Fri, Jul 14, 2028 in Civitavecchia
from $3,849 $183 a night · per person
interior, as of 2026-11-04
AUG
4
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Ibiza (Spain) · Marseille (France) · Calvi (France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Palma de Mallorca (Spain)
Returns Fri, Aug 25, 2028
from $3,599 $171 a night · per person
interior, as of 2026-11-04
AUG
25
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Ibiza (Spain) · Marseille (France) · Santa Margherita (Italy) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Bari (Italy) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Naples (Italy)
Returns Fri, Sep 15, 2028
from $3,649 $174 a night · per person
interior, as of 2026-11-04
SEP
15
Friday · 21 nights
Terminal not published yet
21-Night Greek Isles and Eastern Mediterranean
Calls at Valencia (Spain) · Marseille (France) · Ajaccio (Corsica, France) · La Spezia (Italy) · Civitavecchia (Italy) · Valletta (Malta) · Korcula (Croatia) · Split (Croatia) · Zadar (Croatia) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Messina (Sicily, Italy) · Palma de Mallorca (Spain)
Returns Fri, Oct 6, 2028
from $3,909 $186 a night · per person
interior, as of 2026-11-04

Months this route sails

May 2027 1 June 2027 1 August 2027 1 October 2027 1 June 2028 1 August 2028 2 September 2028 1

Other routes Queen Elizabeth runs

Full ship schedule

14-Night Greek Isles and Eastern Mediterranean Valletta (Malta) · Split (Croatia) · Zadar (Croatia) · Messina (Sicily, Italy) · La Spezia (Italy) · Civitavecchia (Italy) · Kotor (Montenegro) · Dardanelles (Turkey) · Valencia (Spain) · Ajaccio (Corsica, France) · Marseille (France) · Piraeus (Greece) · Istanbul (Turkey) · Ephesus (Turkey) · Katakolon (Greece) · Trieste (Italy) · Dubrovnik (Croatia) · Corfu (Greece) · Naples (Italy) · Santa Margherita (Italy) · Ibiza (Spain) · Mykonos (Greece) · Sorrento (Italy) · Palma de Mallorca (Spain) · Kefalonia (Greece) · Rhodes (Greece) · Calvi (France) · Bari (Italy) · Korcula (Croatia) 9 departures, 9 port combinations from $1,559 7-Night Greek Isles and Eastern Mediterranean Messina (Sicily, Italy) · Piraeus (Greece) · Dardanelles (Turkey) · Valletta (Malta) · Kotor (Montenegro) · Split (Croatia) · Zadar (Croatia) 4 departures, 2 port combinations from $1,019 7-Night Western Mediterranean La Spezia (Italy) · Valencia (Spain) · Ajaccio (Corsica, France) · Marseille (France) · Santa Margherita (Italy) · Ibiza (Spain) · Palma de Mallorca (Spain) · Calvi (France) 5 departures, 5 port combinations from $1,139

Starting fares in US dollars per person, for the cheapest cabin listed, with taxes and port fees included, checked 2026-11-04. Fares change often, so check the current price before you book.

Same region, different ship

All Greek isles and eastern Mediterranean sailings

7-Night Italy & France Explorer of the Seas 14-Night Eastern Mediterranean Costa Favolosa 7-Night Western Mediterranean Oosterdam 21-Night Mediterranean Sun Princess

Queen Elizabeth's 21-Night Greek Isles and Eastern Mediterranean cruise: questions

When does Queen Elizabeth's 21-Night Greek Isles and Eastern Mediterranean cruise leave Barcelona?

Queen Elizabeth's 21-Night Greek Isles and Eastern Mediterranean cruise has 8 departures from Barcelona between May 2027 and September 2028. All of them leave on a Friday.

Which ports does Queen Elizabeth's 21-Night Greek Isles and Eastern Mediterranean cruise from Barcelona call at?

Every departure calls at Civitavecchia and Zadar. The rest depends on the date: via Mykonos on 1 departure, via Palma de Mallorca and Kefalonia on 1 departure, and via Ajaccio and Ibiza on 1 departure, plus 5 other combinations. The cards above list the dates for each.

How much does Queen Elizabeth's 21-Night Greek Isles and Eastern Mediterranean cruise from Barcelona cost?

The lowest starting fare we recorded is $2,589 per person, for the cheapest cabin listed, with taxes and port fees included, on the 21-night sailing of Fri, Jun 11, 2027, about $123 a night. We checked it on November 4, 2026. Fares change daily, so check the current price before you book.