Nieuw Amsterdam at Canada Place, Vancouver, in May 2026

21-Night Western Mediterranean from Barcelona on Nieuw Amsterdam

Nights: 21
Ports of call: 14 to 16
Departures: 4
From: $3,399

Nieuw Amsterdam sails this route from the Port of Barcelona 4 times in the window we track. Each one runs 21 nights. It finishes in Trieste (Italy) rather than back in Barcelona, so check flights home before you book.

Every sailing calls at Livorno (Italy), Civitavecchia (Italy), Naples (Italy), and Piraeus (Greece). The other ports change with the date: there are 2 port combinations, each listed below with its own departure dates. We record which ports a sailing visits, not the order it visits them in.

Departures run from Thu, May 4, 2028 to Sun, Aug 6, 2028. The cheapest recorded starting fare is $3,399 per person, which works out at $162 a night.

Our Mediterranean guide covers which Italian, French and Greek ports each length of cruise reaches, and how the lines differ.

Schedule last updated 2026-11-04 · 4 departures listed · Dates can change. Verify with the cruise line before booking.

Which ports, on which dates?

Via Villefranche

Calls at Villefranche (France) · Livorno (Italy) · Civitavecchia (Italy) · Naples (Italy) · Taormina (Sicily, Italy) · Souda Bay (Crete, Greece) · Rhodes (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kusadasi (Turkey) · Istanbul (Turkey) · Mykonos (Greece) · Souda Bay (Crete, Greece) · Katakolon (Greece) · Sarande (Albania) · Dubrovnik (Croatia)

1 departure, from $4,069 per person

Thu, May 4, 2028

Via Valletta

Calls at Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar

3 departures, from $3,399 per person

Sun, Jun 25, 2028
Sun, Jul 16, 2028
Sun, Aug 6, 2028

Every departure on this route

We may earn a commission if you book through these buttons, at no cost to you.

21-Night Western Mediterranean departures on Nieuw Amsterdam
Departs	Nights	Itinerary & ports	From
Thu, May 4, 2028 ends Thu, May 25, 2028 Terminal not published yet	21	21-Night Western Mediterranean Calls at Villefranche (France) · Livorno (Italy) · Civitavecchia (Italy) · Naples (Italy) · Taormina (Sicily, Italy) · Souda Bay (Crete, Greece) · Rhodes (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kusadasi (Turkey) · Istanbul (Turkey) · Mykonos (Greece) · Souda Bay (Crete, Greece) · Katakolon (Greece) · Sarande (Albania) · Dubrovnik (Croatia) Ends in Trieste (Italy)	from $4,069 $194 a night · per person interior, as of 2026-11-04
Sun, Jun 25, 2028 back Sun, Jul 16, 2028 Terminal not published yet	21	21-Night Western Mediterranean Calls at Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar	from $3,699 $176 a night · per person interior, as of 2026-11-04
Sun, Jul 16, 2028 back Sun, Aug 6, 2028 Terminal not published yet	21	21-Night Western Mediterranean Calls at Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar	from $3,719 $177 a night · per person interior, as of 2026-11-04
Sun, Aug 6, 2028 back Sun, Aug 27, 2028 Terminal not published yet	21	21-Night Western Mediterranean Calls at Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar	from $3,399 $162 a night · per person interior, as of 2026-11-04 Lowest fare shown

MAY
4
Thursday · 21 nights
Terminal not published yet
21-Night Western Mediterranean
Calls at Villefranche (France) · Livorno (Italy) · Civitavecchia (Italy) · Naples (Italy) · Taormina (Sicily, Italy) · Souda Bay (Crete, Greece) · Rhodes (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kusadasi (Turkey) · Istanbul (Turkey) · Mykonos (Greece) · Souda Bay (Crete, Greece) · Katakolon (Greece) · Sarande (Albania) · Dubrovnik (Croatia)
Ends in Trieste (Italy)
Ends Thu, May 25, 2028 in Trieste
from $4,069 $194 a night · per person
interior, as of 2026-11-04
JUN
25
Sunday · 21 nights
Terminal not published yet
21-Night Western Mediterranean
Calls at Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar
Returns Sun, Jul 16, 2028
from $3,699 $176 a night · per person
interior, as of 2026-11-04
JUL
16
Sunday · 21 nights
Terminal not published yet
21-Night Western Mediterranean
Calls at Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar
Returns Sun, Aug 6, 2028
from $3,719 $177 a night · per person
interior, as of 2026-11-04
AUG
6
Sunday · 21 nights
Terminal not published yet
21-Night Western Mediterranean
Calls at Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Naples (Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar
Returns Sun, Aug 27, 2028
Lowest fare shown
from $3,399 $162 a night · per person
interior, as of 2026-11-04

Months this route sails

May 2028 1 June 2028 1 July 2028 1 August 2028 1

Other routes Nieuw Amsterdam runs

Full ship schedule

14-Night Western Mediterranean Valletta (Malta) · Naples (Italy) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Piraeus (Greece) · Kotor (Montenegro) · Kefalonia (Greece) · Messina (Sicily, Italy) · Alicante (Spain) · La Goulette (Tunisia) · Catania (Sicily, Italy) · Civitavecchia (Italy) · Livorno (Italy) · Portofino (Italy) · Marseille (France) · Gibraltar 5 departures, 2 port combinations from $2,264 7-Night Western Mediterranean Valletta (Malta) · Souda Bay (Crete, Greece) · Santorini (Greece) · Kusadasi (Turkey) · Alicante (Spain) · La Goulette (Tunisia) · Catania (Sicily, Italy) · Naples (Italy) 5 departures, 2 port combinations from $1,169

Starting fares in US dollars per person, for the cheapest cabin listed, with taxes and port fees included, checked 2026-11-04. Fares change often, so check the current price before you book.

Same region, different ship

All Greek isles and eastern Mediterranean sailings

7-Night Italy & France Explorer of the Seas 14-Night Greek Isles and Eastern Mediterranean Queen Elizabeth 14-Night Eastern Mediterranean Costa Favolosa 21-Night Greek Isles and Eastern Mediterranean Queen Elizabeth

Nieuw Amsterdam's 21-Night Western Mediterranean cruise: questions

When does Nieuw Amsterdam's 21-Night Western Mediterranean cruise leave Barcelona?

Nieuw Amsterdam's 21-Night Western Mediterranean cruise has 4 departures from Barcelona between May 2028 and August 2028. Most leave on a Sunday, 3 of the 4.

Which ports does Nieuw Amsterdam's 21-Night Western Mediterranean cruise from Barcelona call at?

Every departure calls at Livorno, Civitavecchia, Naples, and Piraeus. The rest depends on the date: via Valletta on 3 departures and via Villefranche on 1 departure. The cards above list the dates for each.

How much does Nieuw Amsterdam's 21-Night Western Mediterranean cruise from Barcelona cost?

The lowest starting fare we recorded is $3,399 per person, for the cheapest cabin listed, with taxes and port fees included, on the 21-night sailing of Sun, Aug 6, 2028, about $162 a night. We checked it on November 4, 2026. Fares change daily, so check the current price before you book.